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Current Location:Home > Products > Knockout Cell Line
KO806464-2

Human MLKL knockout HEK293 cell line

Cat No. : KO806464-2
Gene Name: MLKL
Gene No.: 197259
NM.: NM_152649.3
KO Cell Line: HEK293
Genome Location: Chromosome 16 74695373-74695729(deletion)
Specification: 10E6cell/tube,2 tubes
Price: $4995
Turnaround Time: 2weeks

  • Product Information
  • Gene function
  • Note To Purchase
Product name: human Gene Knockout HEK293 Cell Line

Specifications: 10E6cell/tube,2tubes

Shipping & Storage Conditions:
Product shipped on dry ice. Upon receiving, please store in Liquid nitrogen for long-term storage.

Product features:Guaranteed gene editating efficiency!!!

Product acceptance instructions:
Upon receiving your cell line, please immediately check whether the cell line is thawed, and if so, please take a picture and notify the company immediately. Please start the experiment as soon as possible after receiving the cell line. If you want to store it for a long time, please transfer it to liquid nitrogen.

Note:If you have any questions about how to use the product, please contact our technical support. Our email address is techsupport@wzbioscience.com.

This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to be inactive because it lacks several residues required for activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (RIP3), which is a key signaling molecule in necroptosis pathway. Inhibitor studies and knockdown of this gene inhibited TNF-induced necrosis. High levels of this protein and RIP3 are associated with inflammatory bowel disease in children. Alternatively spliced transcript variants have been described for this gene.

WZ Biosciences' products are to be used only for research purpose only. They may not be used for any other purposes, including, but not limited to, in vitro diagnostic purposes, therapeutics, or in humans.


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