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Human mirRNA Clone

Introduction：

microRNAs(miRNA) are a class of endogenous small non-coding single stranded RNAs. One miRNA could regulate multiple protein translation thus regulates broad biological properties. miRNA is highly conserved among species and matured miRNA is approximately 21-24 nucleotides in length. Their roles in diseases, tissue remodeling and cell differentiation have elicited great interest. WZ Biosciences offers over 1,200 human miRNA clones. Human pri-miRNAs were cloned in the pMIR, a special designed mirRNA expression vector. The expression cassette is driven by a CMV promoter and miRNA is expressed as the 3' UTR of GFP.

Key Features：

•Ready to be shuttled into more than 50 destination vectors, including adenoviral, lentiviral and adeno-associated virus vectors;

•large collection-1,200 Human mirRNA clones;

•Ideal for adenoviral backbone vectors recombination & adenovirus producttion;

•Full sequence verified by NextGen Sequencing;

•Competitive price;

•Ready to use and available for next-day delivery.

Ordering Process：

Delivery Specifications：

500 ul Glycerol Stock

Related Resources：

《Transfection Reagent Instructions》

Customer Published Papers：

1.	Pharmacological Research.(IF=5.893) .Huang et al. (2020) .MiR-377-3p suppresses colorectal cancer through negative regulation on Wnt/β-catenin signaling by targeting XIAP and ZEB2.
2.	PPAR Research.(IF=2.953) .Xu et al. (2019) .Peroxisome Proliferator-Activated Receptor-γ Antagonizes LOX-1-Mediated Endothelial Injury by Transcriptional Activation of miR-590-5p.
3.	Theranostics.(IF=8.579) .Song et al. (2019) .Localized injection of miRNA-21-enriched extracellular vesicles effectively restores cardiac function after myocardial infarction.